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The intersection of GLP-1s and Food Addiction

GLP-1s can be vital added tool for Food Addicts

Recommendations

For all patients

A careful review of the research literature suggests the following recommendations for those patients prescribed these medications. * (summary of cautions and recommendations for weight loss)

  1. Determine adequate intake of protein to minimize and/or prevent muscle loss. Recommendations range from 1.2 to 1.6 grams per kilogram of body weight per day.
  2. Focus on a food plan that significantly limits or eliminates Ultra-Processed Foods. Be aware that these medications may limit your ability to judge your hydration and nutritional needs.
  3. Choose calorie-dense foods or small-volume meals if you experience delayed gastric emptying or feel too full or nauseated. 
  4. Incorporate a reasonable exercise program consisting of both aerobic and resistance (strength) training to minimize or prevent lean tissue loss.
  5.  Participate in online and in-person support groups and counseling, and monitor physical status regularly, including measuring lipids, body weight, and overall health.
  6. Follow the prescribing provider’s dosing schedule, adjustments, and instructions.
  7.  Do not discontinue the medication without consulting your healthcare professional. Contact them if you experience severe symptoms as outlined by the accompanying information from the provider/pharmacy.

For patients experiencing Food Addiction or eating disorders

  1.  Individuals who consider themselves to be Food Addicts and meet the established FDA criteria for these medications (BMI above 27 and a co-existing health issue related to their BMI, or BMI above 30) should not seek to obtain these medications unless they have:
    1. Tried and failed to adhere to an “abstinent” food plan.”
    2. Followed the tenets of a support program or treatment regime without success.
    3. Experienced repeated episodes of relapse despite their best efforts to remain” abstinent.”  
  2.  Eating Disorder patients have an inherent risk of developing an exacerbated version of the existing eating disorder. They should:
    1. Seek an in-depth consultation with an eating disorder specialist before taking these medications.
    2. Request monitoring on a weekly basis during the initial 60-90 days of taking these medications.
    3. Demonstrate an ability to maintain a stable and agreed-upon BMI during this time.
    4. Continue regular counseling and monitoring while taking a GLP-1 medication.
  3. These medications should not be considered for patients with a history of anorexia.
  4. Individualized micro-dosing can be considered for patients who are successful with adhering to an FA-abstinent program, but who still struggle with “food noise” and experience periodic lapses with overeating. Doing so warrants caution and a provider with experience working with “off-label” GLP-1 meds in patients with FAs and certain EDs.
  5. Lifestyle prescriptions include SMERF (Support, Meditation, Exercise, Rest, and a Food Plan). These components address the need to manage the physical, emotional, and spiritual aspects, thereby increasing the likelihood of long-term recovery.

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