Tobore, T. O. (2020). Towards a comprehensive theory of obesity and a healthy diet: The causal role of oxidative stress in food addiction and obesity. Behavioural Brain Research, 384
, 112560. https://doi.org/10.1016/j.bbr.2020.112560
From the research article’s abstract: “Background: Obesity is a major public health problem whose prevalence has been rapidly increasing in the United States (U.S), and globally. It is one of the leading causes of preventable deaths globally and contributes to the development of many diseases. Methods: The search was limited to studies published in English and other languages involving both animal and human subjects. Articles selected included preclinical studies, randomized clinical trials RCTs, observational studies, meta-analyses, narrative and systemic reviews providing primary quantitative data with a measure of obesity or food addiction as an outcome. Over 5000 articles were found in the first round of search which was filtered to 506 articles. Results: Oxidative stress plays a critical role in food addiction and is both a cause and mediator of obesity.