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A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to food addiction

Domingo-Rodriguez, L., et al. (2020). A specific prelimbic-nucleus accumbens pathway controls resilience versus vulnerability to food addiction. Nat Commun, 11(1), 782. https://doi.org/10.1038/s41467-020-14458-y

From the experimental study’s abstract: “We report that the lack of cannabinoid type-1 receptor prevents the development of food addiction-like behavior. In contrast, chemogenetic inhibition of neuronal activity in the mPFC-NAc pathway induces compulsive food seeking.”

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